The use of a chirally selective capillary electrophoresis method is reported for the enantioselective purity determination of propranolol drug substance. The method employed a combination of both charged and neutral cyclodextrin. An internally coated capillary was used to suppress electroosmotic flo
Enantiomeric purity determination of propranolol by cyclodextrin-modified capillary electrophoresis
β Scribed by M. Fillet; I. Bechet; P. Chiap; Ph. Hubert; J. Crommen
- Book ID
- 107785696
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 418 KB
- Volume
- 717
- Category
- Article
- ISSN
- 1873-3778
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## Abstract The enantiomeric separations of several very hydrophobic dihydrofuroflavones were performed and optimized using cyclodextrinβmodified micellar capillary electrophoresis. Overall, the greatest enantiomeric peakβtoβpeak separations for the greatest number of flavones were obtained with hy