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Enantioefficient Synthesis of α-Ergocryptine: First Direct Synthesis of (+)-Lysergic Acid (I).

✍ Scribed by Istvan Moldvai; Eszter Temesvari-Major; Maria Incze; Eva Szentirmay; Eszter Gacs-Baitz; Csaba Szantay

Publisher
John Wiley and Sons
Year
2005
Weight
10 KB
Volume
36
Category
Article
ISSN
0931-7597

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Bromocryptine (2-brom-a-ergocryptine, I) has been found t o be a dopamine agonist used f o r treatment of endocrine disorders and more recently f o r the treatment of Parkinsonism (12'). metabolism and pharmacokinetic studies, a radiolabelled drug was desired. Recent studies have demonstrated the u