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Empirical Bayes analysis of single nucleotide polymorphisms

✍ Scribed by Holger Schwender; Katja Ickstadt


Book ID
115001220
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
408 KB
Volume
9
Category
Article
ISSN
1471-2105

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There is a growing demand for high-throughput methods for analysis of single-nucleotide polymorphic (SNP) positions. Here, we have evaluated a novel sequencing approach, pyrosequencing, for such purposes. Pyrosequencing is a sequencing-by-synthesis method in which a cascade of enzymatic reactions yi