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Emerging roles of ATF2 and the dynamic AP1 network in cancer

✍ Scribed by Lopez-Bergami, Pablo; Lau, Eric; Ronai, Ze'ev


Book ID
109948528
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
92 KB
Volume
10
Category
Article
ISSN
1474-1776

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## Abstract Deubiquitinases (DUBs) are emerging as important regulators of many pathways germane to cancer. They may regulate the stability of key oncogenes, exemplified by USP28 stabilisation of c‐Myc. Alternatively they can negatively regulate ubiquitin‐dependent signalling cascades such as the N