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Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3

✍ Scribed by J. Wesley Pike; Mark B. Meyer; Melissa L. Martowicz; Kathleen A. Bishop; Seong Min Lee; Robert D. Nerenz; Paul D. Goetsch


Book ID
116698462
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
620 KB
Volume
121
Category
Article
ISSN
0960-0760

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The unique hereditary enamel defect clearly related to the disturbance of one enamel matrix protein is X-linked amelogenesis imperfecta (AI), in which several mutations of amelogenin gene have been identified. The clinical phenotype of many of these subjects shows similarities with enamel defects re