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Embryonic ventral mesencephalic grafts improve levodopa-induced dyskinesia in a rat model of Parkinson's disease

✍ Scribed by Lee, C. S.

Book ID: 118049695
Publisher: Oxford University Press
Year: 2000
Tongue: English
Weight: 625 KB
Volume: 123
Category: Article
ISSN: 0006-8950
DOI: 10.1093/brain/123.7.1365

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## Abstract Overactive AMPA receptor‐mediated transmission may be involved in the pathogenesis of levodopa‐induced dyskinesia. The mechanism of action of the anticonvulsant drug topiramate involves attenuation of AMPA receptor‐mediated transmission. In this study, the potential antidyskinetic actio