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3.151 EVALUATION OF TWO EXPERIMENTAL DESIGNS FOR LEVODOPA-INDUCED DYSKINESIA IN A RAT MODEL OF PARKINSON'S DISEASE

✍ Scribed by E. Ivanova; I. Kapitsa; A. Nepoklonov; I. Kokshenev


Book ID
117755233
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
74 KB
Volume
18
Category
Article
ISSN
1353-8020

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## Abstract Overactive AMPA receptor‐mediated transmission may be involved in the pathogenesis of levodopa‐induced dyskinesia. The mechanism of action of the anticonvulsant drug topiramate involves attenuation of AMPA receptor‐mediated transmission. In this study, the potential antidyskinetic actio