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Embryonic Stem Cells and Gene Targeting

✍ Scribed by Birgit Ledermann

Book ID
111112046
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
236 KB
Volume
85
Category
Article
ISSN
0958-0670

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## Abstract Mouse embryonic stem cell lines offer an attractive route for introducing rare genetic alternations into the gene pool since the cells can be pre‐screened in culture and the mutations then transmitted into the germline through chimera production. Two applications of this technique seem