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Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death

✍ Scribed by Hiroshi Yamashita; Takeshi Nakamura; Tetsuya Takahashi; Yoshito Nagano; Masanori Hiji; Takahiro Hirabayashi; Taku Amano; Takeshi Yagi; Norio Sakai; Tatsuo Kohriyama; Masayasu Matsumoto

Book ID
111179518
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
719 KB
Volume
98
Category
Article
ISSN
0022-3042

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✍ Sandrine Bretaud; Claire Allen; Phillip W. Ingham; Oliver Bandmann πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 923 KB

## Abstract Mutations in __DJ‐1__ lead to early onset Parkinson's disease (PD). The aim of this study was to elucidate further the underlying mechanisms leading to neuronal cell death in __DJ‐1__ deficiency __in vivo__ and determine whether the observed cell loss could be prevented pharmacologicall