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Embryolethality of butyl benzyl phthalate during early pregnancy in rats

✍ Scribed by Makoto Ema; Reiko Kurosaka; Hiro Amano; Yoshiyuki Ogawa


Book ID
113384313
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
521 KB
Volume
8
Category
Article
ISSN
0890-6238

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## Abstract Pregnant Wistar rats were given butyl benzyl phthalate (BBP) at a dose of 2.0% in the diet on days 0–20, days 0–11 or days 11–20 of pregnancy. Food consumption and body weight gain were decreased in pregnant rats given BBP. Pre‐implantation loss in the BBP‐treated groups was comparable

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The embryolethality of butyl benzyl phthalate (BBP) was studied in Wistar rats. Pregnant rats were given BBP at dosages of 0 (control) and 2.0% in the diet from day 0 to day 20 of pregnancy. Daily intake of BBP was 974 mg kg-1 for the 2.0% BBP group. In this group, all dams exhibited complete resorp