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Embryo vitrification affects the methylation of the H19/Igf2 differentially methylated domain and the expression of H19 and Igf2

✍ Scribed by Zengyan Wang; Ling Xu; Fangfang He


Book ID
116476829
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
354 KB
Volume
93
Category
Article
ISSN
1556-5653

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Allele specific timing of replication is believed to be a hallmark of imprinted genes, however recent evidence suggests that this might not be the case for the insulin-like growth factor 2 (Igf2) and H19 locus. In this report, we assayed the timing of replication of Igf2 and H19 in two mouse embryon