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CpG methylation regulates the Igf2/H19 insulator

✍ Scribed by Claes Holmgren; Chandrasekhar Kanduri; Ghislaine Dell; Andrew Ward; Rituparna Mukhopadhya; Meena Kanduri; Victor Lobanenkov; Rolf Ohlsson


Book ID
114318410
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
167 KB
Volume
11
Category
Article
ISSN
0960-9822

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## Abstract The mouse insulin‐like growth factor II (__Igf2__) and __H19__ genes are located adjacent to each other on chromosome 7q11‐13 and are reciprocally imprinted. It is believed that the allelic expression of these two genes is regulated by the binding of CTCF insulators to four parent‐speci