Elucidation of the conformations and absolute configurations of enantiomerically pure tetralin derivatives

✍ Scribed by Gábor Tóth; András Simon; Torsten Linker; Frank Rebien; Jürgen Kraus; Gerhard Bringmann

• Book ID: 101251730
• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 184 KB
• Volume: 37
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/(sici)1097-458x(199901)37:1<53::aid-mrc415>3.0.co;2-e

✦ Synopsis

The enantioselective epoxidation of 1,2-dihydronaphthalenes (2) a †orded optically active tetralin derivatives (3 and 4). The relative conÐgurations and conformational behavior of all products were elucidated by detailed one-and two-dimensional 1H and 13C NMR methods. The last required stereochemical information, the absolute conÐguration of 4, attained through comparison of experimental and calculated CD spectra.