Lymphotoxin and tumor necrosis factor provide essential signals for the formation of secondary lymphoid tissue structures. Lymphotoxin in its membrane form (LT alpha 1 beta 2 heterotrimer) is required for the development of lymph nodes and Peyer's patches and supports the development of normal splee
Elucidating the functional anatomy of secondary lymphoid organs
✍ Scribed by Oliver Pabst; Heike Herbrand; Günter Bernhardt; Reinhold Förster
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 381 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
✦ Synopsis
Functional anatomy offers an attempt to exploit anatomical information as a platform from which to decipher mechanistic details of complex or multistep immunological processes. Immune function depends on structural organization, therefore this approach contributes to a comprehensive understanding of the immune system. Major advances in functional anatomy require progress in both experimental techniques and analytical equipment -largely synonymous to refinement of the anatomist's favorite tool, the microscope. Here, we describe how currently available techniques co-operate to gain new insights into the biology of secondary lymphoid organs.
📜 SIMILAR VOLUMES
## Abstract Tuberculosis causes 2 million deaths __per__ year, yet in most cases the immune response successfully contains the infection and prevents disease outbreak. Induced lymphoid structures associated with pulmonary granuloma are observed during tuberculosis in both humans and mice and could
## Abstract In the dragonfly __Tramea virginia__, the secondary copularoty apparatus (SCA) on the venter of the second and third abdominal segments consists of the anterior and posterior laminae, a pair of gential lobes and hamules, the ligula, genital fossa, supporting frame work, and the four seg