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ELF magnetic fields induce internalization of gap junction protein connexin 43 in Chinese hamster lung cells

โœ Scribed by Q.L. Zeng; H. Chiang; G.L. Hu; G.G. Mao; Y.T. Fu; D.Q. Lu


Book ID
101707896
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
99 KB
Volume
24
Category
Article
ISSN
0197-8462

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The effects of extremely low frequency (ELF) magnetic ยฎeld on gap junctional intercellular communication (GJIC), protein levels, and phosphorylation of connexin43 (Cx43) were studied in NIH3T3 cells. The suppression of GJIC by 24 h, 50 Hz, 0.8 mT ELF magnetic ยฎeld, 2 h, 3 ng/ml 12-O-tetradecanoylpho

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## Abstract Numerous studies have demonstrated a correlation between dysregulation/loss of connexin expression or gap junction intercellular communication (GJIC) function and decreased growth control both in human tumors and tumor cell lines. Likewise, restoration of constitutive connexin expressio