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Elevation of metallothionein gene expression associated with hepatic copper accumulation in Long-Evans Cinnamon mutant rat

โœ Scribed by Takahisa Yamada; Yasuo Suzuki; Takashi Agui; Kozo Matsumoto


Book ID
113262569
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
493 KB
Volume
1131
Category
Article
ISSN
0167-4781

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Decreased expression of liver glutathion
โœ Hiroshi Suemizu; Shinichi Yoshimura; Noritoshi Takeichi; Tetsuya Moriuchi ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 731 KB

The Long-Evans Cinnamon rat is a mutant strain that contracts hereditary hepatitis and, eventually, spontaneous hepatoma. Recently, abnormal copper accumulations in Long-Evans Cinnamon rat livers were shown to be genetically linked to the development of hepatitis. Because reduced glutathione and glu