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Elevated second-trimester maternal serum hCG in patients undergoing haemodialysis

✍ Scribed by Po-Jen Cheng; Ching-Ming Liu; Shuenn-Dyh Chang; Yu-Ting Lin; Yung-Kwei Soong

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
102 KB
Volume
19
Category
Article
ISSN
0197-3851

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✦ Synopsis

Prenatal Down syndrome screening with maternal serum alpha-fetoprotein (AFP) and human chorionic gonadotrophin (hCG) has become common. High levels of maternal serum hCG and low levels of AFP have been associated with an increased risk of fetal Down syndrome. In this paper, we report five pregnancies in patients undergoing long-term haemodialysis, all of whom had false-positive second-trimester Down syndrome screening results. All of our five patients had extremely high levels of maternal serum hCG, but normal AFP values for their gestational age, and all had serious complications during pregnancy.

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