correctly normalize urine data. The tighter distribution of hyperglycosylated hCG measurements in serum may compensate for the lesser elevation of values in Down syndrome cases. Hyperglycosylated hCG determinations might be equally useful in urine and serum samples. 60 per cent sensitivity is sugges
ELEVATED MATERNAL SERUM AND AMNIOTIC FLUID ALPHA-FETOPROTEIN LEVELS IN THE DENYS–DRASH SYNDROME
✍ Scribed by KOENRAAD DEVRIENDT; KAMIEL VAN DEN BERGHE; PHILIPPE MOERMAN; JEAN-PIERRE FRYNS
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 237 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0197-3851
No coin nor oath required. For personal study only.
✦ Synopsis
We report the findings in a child with the Denys-Drash syndrome presenting prenatally with a diaphragmatic hernia, male pseudohermaphroditism, and elevated alpha-fetoprotein levels in amniotic fluid and in maternal serum.
📜 SIMILAR VOLUMES
In a study of amniotic fluid from 91 Down syndrome cases and 240 controls, we have shown that the median value of CA125 in pregnancies affected by Down syndrome on the whole reflects those observed in the maternal serum from 106 affected cases and 238 controls. The median MOM for CA125 in amniotic f
Fetal cells are present in the circulation of pregnant women and can be isolated using density gradient centrifugation and magnetic cell sorting. In the present study, maternal cell preparations were depleted for CD45and CD14-positive cells and enriched for CD71-positive cells. The number of fetal n