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Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors

✍ Scribed by Joice M. Cunha; Corinne G. Jolivalt; Khara M. Ramos; Joshua A. Gregory; Nigel A. Calcutt; Andrew P. Mizisin


Book ID
119325849
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
238 KB
Volume
57
Category
Article
ISSN
1532-8600

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Aldose reductase inhibition with imirest
✍ A. L. Carrington; C. B. Ettlinger; N. A. Calcutt; D. R. Tomlinson πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 633 KB

This study describes reduced motor nerve conduction velocity and increased resistance to hypoxia-induced conduction failure in sciatic nerves of rats after four weeks of streptozotocin-induced diabetes (both effects were significant at p < 0.05). These changes occurred in the absence of any deficit