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Depletion of substance P and calcitonin gene-related peptide in sciatic nerve of rats with experimental diabetes; effects of insulin and aldose reductase inhibition

โœ Scribed by Diemel, L.T.; Stevens, E.J.; Willars, G.B.; Tomlinson, D.R.


Book ID
121992885
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
366 KB
Volume
137
Category
Article
ISSN
0304-3940

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Aldose reductase inhibition with imirest
โœ A. L. Carrington; C. B. Ettlinger; N. A. Calcutt; D. R. Tomlinson ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 633 KB

This study describes reduced motor nerve conduction velocity and increased resistance to hypoxia-induced conduction failure in sciatic nerves of rats after four weeks of streptozotocin-induced diabetes (both effects were significant at p < 0.05). These changes occurred in the absence of any deficit