Elevated levels of interleukin-8 in blister fluid of bullous pemphigoidcompared with suction blisters of healthy control subjects
✍ Scribed by Enno Schmidt; Andreas Ambach; Boris Bastian; Eva-Bettina Bröcker; Detlef Zillikens
- Book ID
- 117395329
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 270 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1097-6787
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## Background: Bullous pemphigoid (bp) often provokes blood and tissue eosinophilia, which suggests that some chemoattractants modulate the eosinophil infiltration in bp. eotaxin, a cc chemokine, strongly attracts eosinophils, and interleukin (il)-5 induces eosinophil differentiation, proliferation
An improved fluorodensitometric assay for the determination of 8methoxypsoralen (8-MOP) in plasma is described. Because of its low limit of detection (below 1 rig/spot) this method is suitable to determine the drug in skin suction blister fluid, too. The standard deviation of the procedure is 6.4 %