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Elevated homocysteine levels in levodopa-treated idiopathic Parkinson's disease: a meta-analysis

โœ Scribed by Hu, X.-W.; Qin, S.-M.; Li, D.; Hu, L.-F.; Liu, C.-F.


Book ID
121727646
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
326 KB
Volume
128
Category
Article
ISSN
0001-6314

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## Abstract Homocysteine, cysteine, and cysteinylโ€glycine are all metabolically interrelated. Levodopa/decarboxylase inhibitor (LD/DCI) administration increases total homocysteine (tHcy) plasma levels. Objectives were to investigate associations between LD/DCI intake, concentrations of tHcy, cystei

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## Abstract Levodopa (Lโ€dopa) administered with a dopadecarboxylase inhibitor (DDI) increases homocysteine plasma levels. This may support the onset of atherosclerosisโ€related disorders and neuropsychiatric complications in patients with Parkinson's disease (PD). This homocysteine elevation is cons