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Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice

✍ Scribed by Paolo Guidetti; Gillian P. Bates; Rona K. Graham; Michael R. Hayden; Blair R. Leavitt; Marcy E. MacDonald; Elizabeth J. Slow; Vanessa C. Wheeler; Ben Woodman; Robert Schwarcz

Book ID: 113812002
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 281 KB
Volume: 23
Category: Article
ISSN: 0969-9961
DOI: 10.1016/j.nbd.2006.02.011

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be related to a lysosomal storage disorder. However, they were unable to identify a specific lysosomal enzyme abnormality. In summary, we have described the pathological features of muscle biopsy specimens from 3 infantile cases of Marinesco-S jogren syndrome. W e have identified an unusual ultrast