Electrosynthesis of α-Arylated β-Substituted Cyclopropylphosphonates. Synthesis of a Phosphonic Analogue of Minalcipran
✍ Scribed by Duquenne, Céline; Goumain, Sophie; Jubault, Philippe; Feasson, Christian; Quirion, Jean-Charles
- Book ID
- 118745906
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 117 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
A stereoselective synthesis of a,@-unsaturated phosphonates based on the reaction of S-(p-oxoa1kyl)dithiophosphates and Se-(p-oxoa1kyl)selenophos- phates with sodium dialkyl phosphites is described.
The enantiopure p-toluenesulfinimines were found to be efficient as chiral imine equivalents in the high temperature Reformatsky-type additions with BrZnCF 2 COOEt affording an efficient approach to the enantiomerically pure a,a-difluoro-bamino acids. High chemical and stereochemical yields (drs>9:1