Synthetic precursors of amino phosphonic acids are aziridinyl phosphonates. These compounds can be prepared through a reaction of phosphonates 2a-e with NsONHCO 2 Et and inorganic bases involving addition of an (ethoxycarbonyl)amino group onto the double bond, via a new and easy procedure.
A novel synthesis of α,β-unsaturated phosphonates
✍ Scribed by Aleksandra SkowrońNska; Piotr Dybowski
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 428 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1042-7163
No coin nor oath required. For personal study only.
✦ Synopsis
A stereoselective synthesis of a,@-unsaturated phosphonates based on the reaction of S-(p-oxoa1kyl)dithiophosphates and Se-(p-oxoa1kyl)selenophos- phates with sodium dialkyl phosphites is described.
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract Heteroconjugate addition of various alkyllithium reagents to α‐silylallenephosphonates 3b,c has been accomplished in high yields. The formation of thiophene‐2‐phosphonates 5, by heteroconjugate addition of organolithium to 3bc, followed by treatment with sulfur dioxide, proceeds in reas