## Abstract The coupling of packed capillary liquid chromatography with electrospray ionization mass spectrometry has yielded an instrument capable of generating molecular weight information from very complex natural protein mixtures. The use of the packed capillary liquid chromatography columns of
Electrospray mass spectrometric characterization of the components of protein mixtures and its application to members of the chemokine family of interleukins
β Scribed by I. Kay; S. Hafizi; R. M. Barr; A. I. Mallet; M. W. Greaves
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 401 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1076-5174
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Electrospray mass spectrometry (ES-MS) has been applied to a variety of zinc O,O'-dialkyldithiophosphate (DTP) derivatives. The neutral Zn(DTP)s compounds were converted to the [Zn@I'P)s]-anions by reaction with excess DTP-and these principal anions are readily observed by ES-MS. Exchange reactions