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Electrophysiological effects of phencyclidine and the sigma agonist ditolylguanidine in the cerebellum of the rat

โœ Scribed by Martha Kim; Paula C. Bickford


Book ID
118956614
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
813 KB
Volume
31
Category
Article
ISSN
0028-3908

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Phencyclidine hydrochloride (PCP), injected subcutaneously into rats 30 rain before exposure to the chemical convulsant flurothyl, raised seizure thresholds in a doserelated manner. The narcotic antagonist naloxone was ineffective in blocking the PCP-induced effect. This anticonvulsant property of P