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Electrophoretic and kinetic studies of a mutant red cell pyrimidine 5'-nucleotidase

✍ Scribed by Fujii Hisaichi; Nakashima Koji; Miwa Shiro; Nomura Koichiro


Book ID
115822752
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
572 KB
Volume
95
Category
Article
ISSN
0009-8981

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πŸ“œ SIMILAR VOLUMES


Electrophoretic and kinetic studies of h
✍ Raymonde Rosa; Henri Rochant; Bernard Dreyfus; Colette Valentin; Jean Rosa πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 418 KB

A new case of a defect in red cell pyrimidine 5'-nucleotide (P5N) activity was found in a large family from Guadeloupe in the West Indies. The propositus presented a characteristic hemolytic anemia with red cell basophilic stippling, an increased GSH level, and a shift of the peak in absorbance of n

Kinetic and electrophoretic studies of h
✍ Kenji Shinohara; Kouichi R. Tanaka πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 292 KB

The mutant enzyme of a patient with hereditary pyrimidine 5'-nucleotidase deficiency was analyzed biochemically. Partially purified by DEAE-Sephadex and concentrated by ultrafiltration, the enzyme had a high Km for the substrate uridine monophosphate. Utilization of the substrate cytidine monophosph