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Electrophilic substitution of imidazo[2,1-b]oxazoles

✍ Scribed by Belew Mekonnen; George Crank

Book ID
104207807
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
643 KB
Volume
53
Category
Article
ISSN
0040-4020

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✦ Synopsis

The electrophilic substitutions of di and tri substituted imidazo[2, l-b]oxazoles were studied. Mannich, bromination, nitration, and the Vilsmeier-Haack formylation reactions occur at position-5 of this ring system to give a range of products in high yield.

πŸ“œ SIMILAR VOLUMES

A new and facile synthesis of imidazo[2,
A new and facile synthesis of imidazo[2,1-b]oxazoles
✍ Belew Mekonnen; George Crank; Donald Craig πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 967 KB

## Abstract An efficient and clean two step procedure for the synthesis of imidazo[2,1‐__b__]oxazoles has been developed from 2‐aminooxazoles using titanium(IV) chloride assisted cyclization, and a variety of imidazo[2,1‐__b__]oxazoles have been synthesized in good yields. The structure of one of t