Electrophilic substitution as a convenient approach to functionalized N-benzyl-1,4-dihydropyridines

✍ Scribed by Aleksandr N Kostyuk; Dmitriy M Volochnyuk; Larisa N Lupihal; Aleksandr M Pinchuk; Andrei A Tolmachev

• Book ID: 104251499
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 114 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)01083-3

✦ Synopsis

The reactivity of 1-benzyl-3-cyano-1,4-dihydropyridine was studied in reactions with electrophilic reagents based on structural analogy of 1,4-dihydropyridines with enamines. Different 5-functionalized derivatives were obtained by direct electrophilic substitution.