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A new synthetic approach to N-substituted 1,4-dihydropyridines

✍ Scribed by Ana I De Lucas; Javier Fernández-Gadea; Nazario Martı́n; Carlos Seoane

Book ID
108371236
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
107 KB
Volume
57
Category
Article
ISSN
0040-4020

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Electrophilic substitution as a convenie
Electrophilic substitution as a convenient approach to functionalized N-benzyl-1,4-dihydropyridines
✍ Aleksandr N Kostyuk; Dmitriy M Volochnyuk; Larisa N Lupihal; Aleksandr M Pinchuk 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 114 KB

The reactivity of 1-benzyl-3-cyano-1,4-dihydropyridine was studied in reactions with electrophilic reagents based on structural analogy of 1,4-dihydropyridines with enamines. Different 5-functionalized derivatives were obtained by direct electrophilic substitution.