Electrophilic Cyclization of 2-(1-Alkynyl)-2-alken-1-ones Using the I2/K3PO4 System: An Efficient Synthesis of Highly Substituted Iodofurans.
β Scribed by Yuanhong Liu; Shaolin Zhou
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 29 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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## Abstract Highly substituted 1,2βallenyl ketones can be easily and efficiently prepared from organometallic reagents and readily available 2β(1βalkynyl)β2βalkenβ1βones. The synthetic application of 1,2βallenyl ketone products was also showcased by palladiumβcatalyzed further transformation.
## Abstract The allenyl ketones are useful synthons for tetrasubstituted allenes and highly substituted furans.