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Electrophilic Cyclization of 2-(1-Alkynyl)-2-alken-1-ones Using the I2/K3PO4 System: An Efficient Synthesis of Highly Substituted Iodofurans.

✍ Scribed by Yuanhong Liu; Shaolin Zhou


Publisher
John Wiley and Sons
Year
2006
Weight
29 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract Highly substituted 1,2‐allenyl ketones can be easily and efficiently prepared from organometallic reagents and readily available 2‐(1‐alkynyl)‐2‐alken‐1‐ones. The synthetic application of 1,2‐allenyl ketone products was also showcased by palladium‐catalyzed further transformation.