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Electrophilic benzylation of the pyridine ring. Action of benzyl chlorides on 2-amino and 2-benzylaminopyridine

✍ Scribed by Piotr Kowalski

Book ID
112130606
Publisher
Journal of Heterocyclic Chemistry
Year
1993
Tongue
English
Weight
386 KB
Volume
30
Category
Article
ISSN
0022-152X

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## Abstract Benzyl halides (I) or ‐tosylates (V) are oxidized to aldehydes under mild Kornblum conditions which then undergo a three‐component reaction with various 2‐aminopyridines (II) and isocyanides (III) to afford title compounds (IV)/ (VI) in high yields.