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Electrophilic azide transfer to chiral enolates. A general approach to the asymmetric synthesis of .alpha.-amino acids

✍ Scribed by Evans, David A.; Britton, Thomas C.


Book ID
115483106
Publisher
American Chemical Society
Year
1987
Tongue
English
Weight
416 KB
Volume
109
Category
Article
ISSN
0002-7863

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A general approach to the asymmetric syn
✍ David A. Evans; Deborah A. Evrad; Scott D. Rychnovsky; Thomas FrΓΌh; William G. W πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 French βš– 289 KB

The asymmetric synthesis of vancomycin-related 0t-azido arylglycines by direct azide transfer methodology is reported. Procedures for the conversion of the azides to N-protected arylglycines are provided. Vancomycin, ristocetin, and related glycopeptide antibiotics 2 contain three to five racemizat