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Electronic and electrostatic aspects of carbonic anhydrase inhibition by sulphonamides

✍ Scribed by M.C. Menziani; M. Cocchi; P.G. De Benedetti

Book ID
113257766
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
718 KB
Volume
256
Category
Article
ISSN
0166-1280

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πŸ“œ SIMILAR VOLUMES

Effect of molecular size on carbonic anh
Effect of molecular size on carbonic anhydrase inhibition by sulfonamides
✍ Kamal Kumar; Mahesh C. Bindal; Prithvi Singh; Satya P. Gupta πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 310 KB

## Abstract The molecular size is found to play an important role in carbonic anhydrase (CA) inhibition by sulfonamides. Significant correlation is obtained between the inhibitory power of __meta__‐substituted analogs and the van der Waals volume (__V__~__w__~) of the substitutents. This provides a