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Electron microscopy of fine-needle aspiration biopsy from extragonadal germ cell tumors

โœ Scribed by G. Dell'Antonio; G. L. Taccagni; M. R. Terreni; B. E. Leone; A. Cantaboni

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
705 KB
Volume
8
Category
Article
ISSN
8755-1039

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โœฆ Synopsis

W e describe five cases of extragonadal germ cell tumor (EGCT) diagnosed by the electron microscope (EM) on cytological material. The clinical diagnosis was incorrect in all cases and EGCT was suspected in two cases: cytological diagnosis by light microscopy confirmed the presence of malignant tumor cells, but did not identify the cytotype/s correctly except in one case. Ultrasonography, laparoscopy, and autopsy (in case 3) excluded a primitive germ cell tumor (GCT). Histology confirmed the E M diagnosis in all cases.

EM, even of scanty or necrotic cytological material, is particularly useful for mediastinal and retroperitoneal masses. In case of

EGCT, E M can identify the different cytotypes and the drfferent ultrastructural subcellular cytotypes and demonstrates a close relation between seminomatous and nonseminomatous GCT,

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