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Electron and scanning force microscopy studies of alterations in supercoiled DNA tertiary structure

✍ Scribed by Dmitry I Cherny; Thomas M Jovin


Book ID
115631363
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
640 KB
Volume
313
Category
Article
ISSN
0022-2836

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Most of the scanning force microscopy (SFM) images of supercoiled DNA on untreated mica thus far reported have not shown tight plectonemic structure seen by electron microscopy, but instead less coiled molecules and sometimes a partly "condensed" state with intimate chain-chain interactions. By obse