When mamalian cells are starved for amino acids, the activity of the A amino acid transport system increases, a phenomenon called adaptive regulation. We have examined the effects of those factors which support Madin-Darby canine kidney (MDCK) cell growth in a defined medium on the derepression of S
Electrogenic transport of neutral and dibasic amino acids in a cultured opossum kidney cell line (OK)
β Scribed by Johann S. Schwegler; Almut Heuner; Stefan Silbernagl
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 836 KB
- Volume
- 414
- Category
- Article
- ISSN
- 0031-6768
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π SIMILAR VOLUMES
## Abstract Amino acid transport in MadinβDarby canine kidney (MDCK) cells, grown in a defined medium, was investigated as a function of cell density, exposure to specific growth factors, and transformation. MDCK cells were found to transport neutral amino acids by systems similar to the A, ASC, L,
Neutral amino acid transport by system A was investigated in the epithelial cell lines MDCK and MDCK-T1. The latter line is a chemically induced, oncogenically transformed line derived from MDCK. Inducers of differentiation, sodium butyrate and 5-azacytidine, and a tumor promoter, TPA, were used as