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Electrochemical synthesis of 2-substituted 5-aminofurans.

✍ Scribed by Martine Largeron; Maurice-Bernard Fleury

Publisher: Elsevier Science
Year: 1991
Tongue: French
Weight: 258 KB
Volume: 32
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)74846-5

No coin nor oath required. For personal study only.

✦ Synopsis

Electrochemical reduction of 2-substituted 5-nttrofurans in neutral hydroalcoholic media leads to the corresponding 5-ammofurans which have been isolated 2Substituted S-nitrofuran denvattves are used as antimicrobial drugs'. Some of them display mutagenic and carcinogenic activity' which is due to the reduction of the nmo group into active metabolites.

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