Electrochemical biosensor for epidermal growth factor receptor detection with peptide ligand
β Scribed by Li, Ruibao; Huang, Huiming; Huang, Liangzhu; Lin, Zhenyu; Guo, Longhua; Qiu, Bin; Chen, Guonan
- Book ID
- 121966142
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 731 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0013-4686
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A rapid and sensitive nonradioactive ligand binding assay for identifying the agonists and antagonists of epidermal growth factor receptor is described. The assay is easy to perform, has a within-assay error of less than 15%, and does not use radioactive substances. Nonspecific binding is less than
The epidermal growth factor receptor (EGFR) is involved in the proliferation and differentiation of normal and malignant cells and is a major therapeutic target for a variety of human cancers. The peptide GE11 was reported to bind efficiently to the EGFR. Labeling GE11 with radionuclides may aid in