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Electrically controlled release of macromolecules from cross-linked hyaluronic acid hydrogels

โœ Scribed by Ron Tomer; Dejana Dimitrijevic; Alexander T. Florence

Book ID
113275642
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
558 KB
Volume
33
Category
Article
ISSN
0168-3659

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We have incorporated daunomycin, an antineoplastic agent, into a biodegradable hydrogel through a labile covalent bond. In brief, sodium alginate was chemically broken down to low molecular weight and followed by oxidation to prepare poly-(aldehyde guluronate). Adipic dihydrazide was used to incorpo