Ein papierchromatographischer Nachweis von 2,4-Dioxo-3,3-di�thyl-5-methylpiperidin (Noludar, Methyprylon)
✍ Scribed by Dressler, Arnold
- Book ID
- 104816365
- Publisher
- Springer-Verlag
- Year
- 1959
- Weight
- 78 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0370-8497
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**The Spontaneous Resolution of the 3,3‐Diethyl‐5‐methylpiperidine‐2,4‐dione (Methyprylon) into its Optical Isomers. An X‐Ray Structure Analysis of an Isodimoophous System of Mixed Crystals** Repeated recrystallizations from acetone of a racemic mixture of the title compound successively result in
## Abstract 2, 4‐Dioxo‐3, 3‐diethyl‐5‐methyl‐piperidine is spontaneously re‐ solved into its optical antipodes by about 400 crystallisations from various solvents e.g. methanol, acetone, butanol, water etc. From the melting point diagram and the behaviour in the resolution process it must be conclu