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Ein neuer Reaktionsweg zu 1, 3-Dicarbonylderivaten. Modelluntersuchungen am A/B-Teil von 3-Oxo-5α-steroiden

✍ Scribed by Hans Berbalk; Karl Eichinger; Willibald Winetzhammer

Publisher: John Wiley and Sons
Year: 1981
Tongue: German
Weight: 377 KB
Volume: 64
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19810640408

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✦ Synopsis

A New Route to 1, 3‐Dicarbonyl Derivatives, Model Investigations on the A/B‐Part of‐3‐Oxo‐5α‐steroids

Starting from 1 the 1, 3‐dicarbonyl compounds 4a–d were synthetized via the enynes 2a–e and the relatively unstable epoxides 3a–d. The latter were reacted with 95% formic acid to gave 4a–d; small amounts of the furane derivatives 5a–c were identified as by‐products in this last step. In the presence of catalytic amounts of HgSO~4~ the epoxides 3a–c yielded with 95% formic acid the furanes 5a–c, but no detectable amounts of 4a–c.

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