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Eighteen new polymorphic markers in the multiple endocrine neoplasia type 1(MEN1)region

✍ Scribed by Pachiappan Manickam; Siradanahalli C. Guru; Larisa V. Debelenko; Sunita K. Agarwal; Shodimu-Emmanuel Olufemi; Jane M. Weisemann; Mark S. Boguski; Judy S. Crabtree; Yingping Wang; Bruce A. Roe; Irina A. Lubensky; Zhengping Zhuang; Mary Beth Kester; A. Lee Burns; Allen M. Spiegel; Stephen J. Marx; Lance A. Liotta; Michael R. Emmert-Buck; Francis S. Collins; S. C. Chandrasekharappa


Publisher
Springer
Year
1997
Tongue
English
Weight
121 KB
Volume
101
Category
Article
ISSN
0340-6717

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Multiple endocrine neoplasia type 1 (MEN
✍ B. T. Teh; S. I. Hii; R. David; V. Parameswaran; S. Grimmond; M. K. Walters; T. πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 453 KB

Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disease characterized by neoplasia of the parathyroid glands, anterior pituitary and endocrine pancreas, is rarely reported in Asian populations. The MEN1 gene, mapped to chromosome 11q13 but yet to be cloned, has been found to be hom

Isolation and mapping of polymorphic cos
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Multiple endocrine neoplasia type 1 (MEN1) is characterized by neoplasia of the parathyroids, the pancreas, and the pituitary. Tumorigenesis involves unmasking of a recessive mutation at the MEN1 locus, which has been mapped to the centromeric part of chromosomal region 11q. In order to localize the