Background. Urokinase-type plasminogen activator is important for matrix degradation and motility of cancer cells. For effective invasion, urokinase has to be associated with its cell surface receptor. 1 Methods. We analyzed 33 head and neck squamous cell carcinomas (hnSCC) and 14 mucosal tissue sam
EGFR Regulates the Side Population in Head and Neck Squamous Cell Carcinoma
β Scribed by Jocelyn S. Chen; Francisco S. Pardo; Jessica Wang-Rodriguez; Theresa S. Chu; Jay Patrick Lopez; Joseph Aguilera; Xabier Altuna; Robert A. Weisman; Weg M. Ongkeko
- Book ID
- 110087950
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 967 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0023-852X
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## Abstract ## Background Germline mutations at the __INK4a/p16__ locus are implicated in several human cancer syndromes, including familial atypical multiple mole melanoma (FAMMM) syndrome, FAMMMβpancreatic cancer (FAMMMβPC) syndrome, and in familial head and neck cancer syndrome. ## Methods We