EGFR Inhibitor Enhances Cisplatin Sensitivity of Oral Squamous Cell Carcinoma Cell Lines
β Scribed by Yukihiro Hiraishi; Takeshi Wada; Ken Nakatani; Itaru Tojyo; Takashi Matsumoto; Norifumi Kiga; Kenji Negoro; Shigeyuki Fujita
- Book ID
- 107636188
- Publisher
- Springer Netherlands
- Year
- 2008
- Tongue
- English
- Weight
- 153 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1219-4956
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Cisplatin is a widely used chemotherapeutic agent in head and neck squamous cell carcinoma (HNSCC). Resistance to cisplatin is a common feature of HNSCC. To identify genes that may regulate cisplatin sensitivity, we carried out a cDNA microarray analysis of gene expression in cisplatin-sensitive and
## Abstract Our study was conducted to investigate whether anticancer drugs, cisplatin (CDDP) and/or 5βfluorouracil (5βFU), can modulate Fasβmediated apoptosis in oral squamous cell carcinoma (OSCC) cell lines. When OSCC cell lines, NA and HSCβ4, were treated with CDDP and/or 5βFU, Fas and its mRNA
## Abstract ## __Background.__ The aim of the current study was to identify the antitumor activity of satraplatin in paired cisplatin (CDDP)βresistant oral squamous cell carcinoma (OSCC) cell line and its parental cell line. ## __Methods.__ CDDPβresistant (KBβR) cells and parental cells (KB) pai