𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Efflux properties of basolateral peptide transporter in human intestinal cell line Caco-2

✍ Scribed by Megumi Irie; Tomohiro Terada; Masahiro Okuda; Ken-ichi Inui


Publisher
Springer
Year
2004
Tongue
English
Weight
219 KB
Volume
449
Category
Article
ISSN
0031-6768

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Transport of levovirin prodrugs in the h
✍ Fujun Li; Lei Hong; Cheng-I Mau; Rebecca Chan; Than Hendricks; Chuck Dvorak; Cal πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 142 KB πŸ‘ 1 views

The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi

Effects of poly(ethylene glycol) on effl
✍ Erin D. Hugger; Kenneth L. Audus; Ronald T. Borchardt πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 285 KB

Poly(ethylene glycol) (PEG) is an excipient commonly used in pharmaceutical formulations to increase the aqueous solubility of drugs intended for oral administration. High concentrations of PEG are often used to solubilize drug candidates for in vitro experiments in cell culture (e.g., Caco-2 cell p