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Efficient Synthesis of Optically Pure 1,1,1-Trifluoro-2-alkanols through Lipase-Catalyzed Acylation in Organic Media

✍ Scribed by Hamada, Hiroki; Shiromoto, Mizuho; Funahashi, Makoto; Itoh, Toshiyuki; Nakamura, Kaoru


Book ID
126884876
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
168 KB
Volume
61
Category
Article
ISSN
0022-3263

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Synthesis of optically active novel 1,1,
✍ Yumiko Takagi; Masaya Kashiwagi; Hiroshi Kihara; Toshiyuki Itoh πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 132 KB

The fn'st synthesis of several types of optically active l,l,2-lrifluoro-1alkea-3-ols has been accomplished through the Pseudomonas cepacia F~ase-catalyzed trans-esterif~ation. The PCL catalyzed acylation using vinyl chloroacetate as the aeyl donor provided the corresponding fiuorinated-allyl alcoho