Efficient synthesis of novel dipyridoimidazoles and pyrido[1′,2′;1,2]imidazo[4,5-d]pyridazine derivatives
✍ Scribed by Jean M Chezal; Emmanuel Moreau; Olivier Chavignon; Claire Lartigue; Yves Blache; Jean C Teulade
- Book ID
- 104205552
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 262 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
pyridazine derivatives 9a -d were synthesized by two pathways: thermal electrocyclic reaction of 3-alkenylimidazopyridine-2-oximes 10 and direct condensation of ethyl glycinate (or hydrazine) with 2,3-dicarbonylimidazo[1,2-a]pyridines 11.
📜 SIMILAR VOLUMES
## Abstract The peak potentials (Ep) of 3‐substituted pyrido[1′,2′:1,2]imidazo[4,5‐__b__]pyrazine and pyrido[1′,2′:1,2]‐imidazo[4,5‐__b__]quinoxaline derivatives are sufficiently correlated with Hammett substituent constant ∼~m~ and with the PM3 calculated LUMO energy levels, and the linear relatio
## Abstract The imidazo[1,2‐__a__]pyridine system was investigated as a synthon for the building of very attractive fused triazines, a planar, angular __tri__‐heterocycle with potential biological activity. Thus ethyl 3‐nitroimidazo[1,2‐__a__]pyridine‐2‐carboxylate was treated with ammonia or with