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Efficient Synthesis of Novel 3-Aryl-5-(4-chloro-2-morpholinothiazol-5-yl)-4,5-dihydro-1 H -pyrazoles and Their Antifungal Activity Alone and in Combination with Commercial Antifungal Agents

✍ Scribed by Ramírez, Juan; Rodríguez, María Victoria; Quiroga, Jairo; Abonia, Rodrigo; Sortino, Maximiliano; Zacchino, Susana A.; Insuasty, Braulio


Book ID
124091039
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
371 KB
Volume
347
Category
Article
ISSN
0365-6233

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Efficient synthesis and dehydration reac
✍ Helio G. Bonacorso; Mauro N. Muniz; Arci D. Wastowski; Nilo Zanatta; Marcos A. P 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB

## Abstract A convenient method for the synthesis of a novel series of 11, specifically substituted, noncondensed 5,5‐bicycles 2‐[3‐phenyl‐5‐hydroxy‐5‐trichloromethyl‐4,5‐dihydro‐1H‐pyrazol‐1‐yl]‐4‐aryl‐5‐alkylthiazoles (**3a–k**; 65–94% yield) from the reactions of 3‐phenyl‐5‐hydroxy‐5‐trichlorome